BMRB Entry 17527

Title:
Structure of epidermal growth factor-like repeat 12 of mouse Notch-1 receptor
Deposition date:
2011-03-16
Original release date:
2011-04-11
Authors:
Hosoguchi, K.; Shimizu, K.; Nishimura, S.-I.
Citation:

Citation: Hiruma-Shimizu, Kazumi; Hosoguchi, Kensaku; Liu, Yan; Fujitani, Naoki; Ohta, Takashi; Hinou, Hiroshi; Matsushita, Takahiko; Shimizu, Hiroki; Feizi, Ten; Nishimura, Shin-ichiro. "Chemical synthesis, folding, and structural insights into O-fucosylated epidermal growth factor-like repeat 12 of mouse Notch-1 receptor."  J. Am. Chem. Soc. 132, 14857-14865 (2010).
PubMed: 20883017

Assembly members:

Assembly members:
NEUROGENIC_LOCUS_NOTCH_HOMOLOG_PROTEIN_1_EGF12_domain, polymer, 38 residues, Formula weight is not available
FUC, non-polymer, Formula weight is not available

Natural source:

Natural source:   Common Name: mouse   Taxonomy ID: 10090   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Mus musculus

Experimental source:

Experimental source:   Production method: chemical synthesis   Host organism: chemical snthesis   Vector: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
NEUROGENIC_LOCUS_NOTCH_HOMOLOG_PROTEIN_1_EGF12_domain: DVNECISNPCQNDATCLDQI GEFQCICMPGYEGVYCEI

Data sets:
Data typeCount
1H chemical shifts253

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1EGF12 peptide1
2FUC2

Entities:

Entity 1, EGF12 peptide 38 residues - Formula weight is not available

The C terminus Isoleucine 38 id not free form from COOH but CONH2

1   ASPVALASNGLUCYSILESERASNPROCYS
2   GLNASNASPALATHRCYSLEUASPGLNILE
3   GLYGLUPHEGLNCYSILECYSMETPROGLY
4   TYRGLUGLYVALTYRCYSGLUILE

Entity 2, FUC - Formula weight is not available

1   FUC

Related Database Links:

BMRB 11006 17528
PDB 2RQZ 2RR0 2RR2