BMRB Entry 17268

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PDB ID: 2l59
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR17268
MolProbity Validation Chart

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Title:
Solution Structures of Oxidized and Reduced Thioredoxin C from M. tb
Deposition date:
2010-10-28
Original release date:
2013-07-01
Authors:
Olson, Andrew; Cai, Sheng; Sem, Daniel
Citation:

Citation: Olson, Andrew; Neumann, Terrence; Cai, Sheng; Sem, Daniel. "Solution structures of Mycobacterium tuberculosis thioredoxin C and models of intact thioredoxin system suggest new approaches to inhibitor and drug design"  Proteins 81, 675-689 (2013).
PubMed: 23229911

Assembly members:

Assembly members:
entity, polymer, 116 residues, 12557.545 Da.

Natural source:

Natural source:   Common Name: Mycobacterium tuberculosis   Taxonomy ID: 1773   Superkingdom: bacteria   Kingdom: not available   Genus/species: Mycobacterium tuberculosis

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET-23b

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity: MTDSEKSATIKVTDASFATD VLSSNKPVLVDFWATWCGPC KMVAPVLEEIATERATDLTV AKLDVDTNPETARNFQVVSI PTLILFKDGQPVKRIVGAKG KAALLRELSDVVPNLN

Data sets:
Data typeCount
13C chemical shifts302
15N chemical shifts104
1H chemical shifts739

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1Thioredoxin C1

Entities:

Entity 1, Thioredoxin C 116 residues - 12557.545 Da.

1   METTHRASPSERGLULYSSERALATHRILE
2   LYSVALTHRASPALASERPHEALATHRASP
3   VALLEUSERSERASNLYSPROVALLEUVAL
4   ASPPHETRPALATHRTRPCYSGLYPROCYS
5   LYSMETVALALAPROVALLEUGLUGLUILE
6   ALATHRGLUARGALATHRASPLEUTHRVAL
7   ALALYSLEUASPVALASPTHRASNPROGLU
8   THRALAARGASNPHEGLNVALVALSERILE
9   PROTHRLEUILELEUPHELYSASPGLYGLN
10   PROVALLYSARGILEVALGLYALALYSGLY
11   LYSALAALALEULEUARGGLULEUSERASP
12   VALVALPROASNLEUASN

Related Database Links:

BMRB 17242
PDB 2I1U 2L4Q 2L59 3NOF 3O6T
DBJ BAH28242 BAL68058 BAQ08156 GAA43797
EMBL CAA65071 CAL70004 CAL73962 CCC28997 CCC46265
GB AAK48398 ABQ75742 ABR08274 ACT27071 AEB06115
REF NP_218431 NP_857580 WP_003400164 WP_015288674 WP_031662639
SP P0A617 P9WG66 P9WG67
AlphaFold P0A617 P9WG66 P9WG67

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