BMRB Entry 17255
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PDB ID: 2l4t
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR17255
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Zoetewey, David; Ovee, Mohiuddin; Banerjee, Monimoy; Bhaskaran, Rajagopalan; Mohanty, Smita. "Promiscuous binding at the crossroads of numerous cancer pathways: insight from the binding of glutaminase interacting protein with glutaminase L." Biochemistry 50, 3528-3539 (2011).
PubMed: 21417405
Assembly members:
Glutaminase_Interacting_Protein_3, polymer, 124 residues, 13751.796 Da.
Glutaminase_L_peptide, polymer, 8 residues, 950.092 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET-3c/GIP
Entity Sequences (FASTA):
Glutaminase_Interacting_Protein_3: MSYIPGQPVTAVVQRVEIHK
LRQGENLILGFSIGGGIDQD
PSQNPFSEDKTDKGIYVTRV
SEGGPAEIAGLQIGDKIMQV
NGWDMTMVTHDQARKRLTKR
SEEVVRLLVTRQSLQKAVQQ
SMLS
Glutaminase_L_peptide: KENLESMV
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 388 |
| 15N chemical shifts | 136 |
| 1H chemical shifts | 930 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | Glutaminase Interacting Protein 3 | 1 |
| 2 | Glutaminase L peptide | 2 |
Entities:
Entity 1, Glutaminase Interacting Protein 3 124 residues - 13751.796 Da.
| 1 | MET | SER | TYR | ILE | PRO | GLY | GLN | PRO | VAL | THR | ||||
| 2 | ALA | VAL | VAL | GLN | ARG | VAL | GLU | ILE | HIS | LYS | ||||
| 3 | LEU | ARG | GLN | GLY | GLU | ASN | LEU | ILE | LEU | GLY | ||||
| 4 | PHE | SER | ILE | GLY | GLY | GLY | ILE | ASP | GLN | ASP | ||||
| 5 | PRO | SER | GLN | ASN | PRO | PHE | SER | GLU | ASP | LYS | ||||
| 6 | THR | ASP | LYS | GLY | ILE | TYR | VAL | THR | ARG | VAL | ||||
| 7 | SER | GLU | GLY | GLY | PRO | ALA | GLU | ILE | ALA | GLY | ||||
| 8 | LEU | GLN | ILE | GLY | ASP | LYS | ILE | MET | GLN | VAL | ||||
| 9 | ASN | GLY | TRP | ASP | MET | THR | MET | VAL | THR | HIS | ||||
| 10 | ASP | GLN | ALA | ARG | LYS | ARG | LEU | THR | LYS | ARG | ||||
| 11 | SER | GLU | GLU | VAL | VAL | ARG | LEU | LEU | VAL | THR | ||||
| 12 | ARG | GLN | SER | LEU | GLN | LYS | ALA | VAL | GLN | GLN | ||||
| 13 | SER | MET | LEU | SER |
Entity 2, Glutaminase L peptide 8 residues - 950.092 Da.
| 1 | LYS | GLU | ASN | LEU | GLU | SER | MET | VAL |
Related Database Links:
| BMRB | 16285 17254 |
| PDB | 2KG2 2L4S 2L4T 2VZ5 3DIW 3DJ1 3DJ3 3GJ9 3SFJ 4E3B 4NNL 4NNM |
| DBJ | BAB23703 BAE29879 BAE40411 BAE41827 BAE89417 |
| GB | AAB84248 AAF43104 AAG44368 AAH08166 AAH23980 |
| REF | NP_001029646 NP_001244463 NP_001272005 NP_055419 NP_083840 |
| SP | O14907 Q9DBG9 |
| TPG | DAA18859 |
| AlphaFold | O14907 Q9DBG9 |
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SPARKY: Backbone
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