BMRB Entry 16893

Title:
MDM4 binds ligands via an induced fit mechanism in which disordered regions become structured
Deposition date:
2010-04-22
Original release date:
2010-06-16
Authors:
Sanchez, Maria; Renshaw, Jonathan; Davies, Gareth; Barlow, Paul; Vogtherr, Martin
Citation:

Citation: Sanchez, Maria; Renshaw, Jonathan; Davies, Gareth; Barlow, Paul; Vogtherr, Martin. "MDM4 binds ligands via a mechanism in which disordered regions become structured."  FEBS Lett. 584, 3035-3041 (2010).
PubMed: 20515689

Assembly members:

Assembly members:
MDM4 N-terminal domain, polymer, 102 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET28b

Entity Sequences (FASTA):

Data sets:
Data typeCount
13C chemical shifts215
15N chemical shifts66
1H chemical shifts66

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1MDM41

Entities:

Entity 1, MDM4 102 residues - Formula weight is not available

1   GLYSERHISMETASPSERALASERARGILE
2   SERPROGLYGLNILEASNGLNVALARGPRO
3   LYSLEUPROLEULEULYSILELEUHISALA
4   ALAGLYALAGLNGLYGLUMETPHETHRVAL
5   LYSGLUVALMETHISTYRLEUGLYGLNTYR
6   ILEMETVALLYSGLNLEUTYRASPGLNGLN
7   GLUGLNHISMETVALTYRCYSGLYGLYASP
8   LEULEUGLYGLULEULEUGLYARGGLNSER
9   PHESERVALLYSASPPROSERPROLEUTYR
10   ASPMETLEUARGLYSASNLEUVALTHRLEU
11   ALATHR

Related Database Links:

BMRB 16894 16900
PDB 2VYR 3DAB 3FDO 3FE7 3FEA 3JZO 3JZP 3JZQ 3LBJ 3U15 4RXZ
DBJ BAD96948 BAG64634 BAG65468 BAK62829
EMBL CAE45961 CAH18300
GB AAH67299 AAI05107 AAO13494 AGJ70143 AGZ93683
REF NP_001191100 NP_001265445 NP_001265447 NP_001267305 NP_002384
SP O15151
AlphaFold O15151

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks