BMRB Entry 15703

Name: Soluble form of human earliest activation antigen of leukocytes CD69
Published: 2008-11-10

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR15703

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Nicholas Rego and David Koes
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Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

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Title:

Soluble form of human earliest activation antigen of leukocytes CD69

Deposition date:

2008-04-01

Original release date:

2008-11-10

Authors:

Kubickova, Monika; Kaderavek, Pavel; Chmelik, Josef; Zidek, Lukas; Sklenar, Vladimir

Citation:

Citation: Vanek, Ondrej; Nalezkova, Monika; Kavan, Daniel; Borovickova, Ivana; Pompach, Petr; Novak, Petr; Kumar, Vinay; Vannucci, Luca; Hudecek, Jiri; Hofbauerova, Katerina; Kopecky, Vladimir; Brynda, Jiri; Kolenko, Petr; Dohnalek, Jan; Kaderavek, Pavel; Chmelik, Josef; Gorcik, Lukas; Zidek, Lukas; Sklenar, Vladimir; Bezouska, Karel. "Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice" FEBS J. 275, 5589-5606 (2008).
PubMed: 18959746

Assembly members:

Assembly members:
CD69, polymer, 130 residues, Formula weight is not available

Natural source:

Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens

Experimental source:

Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pRSETB

Entity Sequences (FASTA):

Entity Sequences (FASTA):
CD69: GQYTFSMPSDSHVSSCSEDW VGYQRKCYFISTVKRSWTSA QNACSEHGATLAVIDSEKDM NFLKRYAGREEHWVGLKKEP GHPWKWSNGKEFNNWFNVTG SDKCVFLKNTEVSSMECEKN LYWICNKPYK

Data sets:

assigned_chemical_shifts
- assigned_chem_shift_list_1
heteronucl_NOEs
- heteronuclear_noe_list_1
heteronucl_T1_relaxation
- heteronuclear_T1_list_1
heteronucl_T2_relaxation
- heteronuclear_T2_list_1

Data type	Count
13C chemical shifts	205
15N chemical shifts	102
1H chemical shifts	102
heteronuclear NOE values	83
T1 relaxation values	83
T2 relaxation values	84

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
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Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	CD69	1

Entities:

Entity 1, CD69 130 residues - Formula weight is not available

1	GLY	GLN	TYR	THR	PHE	SER	MET	PRO	SER	ASP
2	SER	HIS	VAL	SER	SER	CYS	SER	GLU	ASP	TRP
3	VAL	GLY	TYR	GLN	ARG	LYS	CYS	TYR	PHE	ILE
4	SER	THR	VAL	LYS	ARG	SER	TRP	THR	SER	ALA
5	GLN	ASN	ALA	CYS	SER	GLU	HIS	GLY	ALA	THR
6	LEU	ALA	VAL	ILE	ASP	SER	GLU	LYS	ASP	MET
7	ASN	PHE	LEU	LYS	ARG	TYR	ALA	GLY	ARG	GLU
8	GLU	HIS	TRP	VAL	GLY	LEU	LYS	LYS	GLU	PRO
9	GLY	HIS	PRO	TRP	LYS	TRP	SER	ASN	GLY	LYS
10	GLU	PHE	ASN	ASN	TRP	PHE	ASN	VAL	THR	GLY
11	SER	ASP	LYS	CYS	VAL	PHE	LEU	LYS	ASN	THR
12	GLU	VAL	SER	SER	MET	GLU	CYS	GLU	LYS	ASN
13	LEU	TYR	TRP	ILE	CYS	ASN	LYS	PRO	TYR	LYS

Name	Sample	Sample state	Sample conditions
2D 1H-15N HSQC	sample_1	isotropic	sample_conditions_1
3D CBCA(CO)NH	sample_1	isotropic	sample_conditions_1
3D HNCACB	sample_1	isotropic	sample_conditions_1
3D HNCA	sample_1	isotropic	sample_conditions_1
3D HN(CO)CA	sample_1	isotropic	sample_conditions_1
T1	sample_2	isotropic	sample_conditions_1
T2	sample_2	isotropic	sample_conditions_1
ssNOE	sample_2	isotropic	sample_conditions_1

PDB	1E87 1E8I 1FM5 3CCK 3HUP
DBJ	BAF84558 BAG64271
EMBL	CAA80298 CAA83017
GB	AAB46359 AAH07037 AAO63584 ABM84101 ABM87473
REF	NP_001772 XP_002822933 XP_003265512 XP_003829696 XP_004052729
SP	Q07108
AlphaFold	Q07108

BMRB Entry 15703

Additional metadata:

Assembly:

Entities:

Samples:

Experiments:

Software:

NMR spectrometers:

Related Database Links:

1	GLY	GLN	TYR	THR	PHE	SER	MET	PRO	SER	ASP
2	SER	HIS	VAL	SER	SER	CYS	SER	GLU	ASP	TRP
3	VAL	GLY	TYR	GLN	ARG	LYS	CYS	TYR	PHE	ILE
4	SER	THR	VAL	LYS	ARG	SER	TRP	THR	SER	ALA
5	GLN	ASN	ALA	CYS	SER	GLU	HIS	GLY	ALA	THR
6	LEU	ALA	VAL	ILE	ASP	SER	GLU	LYS	ASP	MET
7	ASN	PHE	LEU	LYS	ARG	TYR	ALA	GLY	ARG	GLU
8	GLU	HIS	TRP	VAL	GLY	LEU	LYS	LYS	GLU	PRO
9	GLY	HIS	PRO	TRP	LYS	TRP	SER	ASN	GLY	LYS
10	GLU	PHE	ASN	ASN	TRP	PHE	ASN	VAL	THR	GLY
11	SER	ASP	LYS	CYS	VAL	PHE	LEU	LYS	ASN	THR
12	GLU	VAL	SER	SER	MET	GLU	CYS	GLU	LYS	ASN
13	LEU	TYR	TRP	ILE	CYS	ASN	LYS	PRO	TYR	LYS

1	GLY	GLN	TYR	THR	PHE	SER	MET	PRO	SER	ASP
2	SER	HIS	VAL	SER	SER	CYS	SER	GLU	ASP	TRP
3	VAL	GLY	TYR	GLN	ARG	LYS	CYS	TYR	PHE	ILE
4	SER	THR	VAL	LYS	ARG	SER	TRP	THR	SER	ALA
5	GLN	ASN	ALA	CYS	SER	GLU	HIS	GLY	ALA	THR
6	LEU	ALA	VAL	ILE	ASP	SER	GLU	LYS	ASP	MET
7	ASN	PHE	LEU	LYS	ARG	TYR	ALA	GLY	ARG	GLU
8	GLU	HIS	TRP	VAL	GLY	LEU	LYS	LYS	GLU	PRO
9	GLY	HIS	PRO	TRP	LYS	TRP	SER	ASN	GLY	LYS
10	GLU	PHE	ASN	ASN	TRP	PHE	ASN	VAL	THR	GLY
11	SER	ASP	LYS	CYS	VAL	PHE	LEU	LYS	ASN	THR
12	GLU	VAL	SER	SER	MET	GLU	CYS	GLU	LYS	ASN
13	LEU	TYR	TRP	ILE	CYS	ASN	LYS	PRO	TYR	LYS

1	GLY	GLN	TYR	THR	PHE	SER	MET	PRO	SER	ASP
2	SER	HIS	VAL	SER	SER	CYS	SER	GLU	ASP	TRP
3	VAL	GLY	TYR	GLN	ARG	LYS	CYS	TYR	PHE	ILE
4	SER	THR	VAL	LYS	ARG	SER	TRP	THR	SER	ALA
5	GLN	ASN	ALA	CYS	SER	GLU	HIS	GLY	ALA	THR
6	LEU	ALA	VAL	ILE	ASP	SER	GLU	LYS	ASP	MET
7	ASN	PHE	LEU	LYS	ARG	TYR	ALA	GLY	ARG	GLU
8	GLU	HIS	TRP	VAL	GLY	LEU	LYS	LYS	GLU	PRO
9	GLY	HIS	PRO	TRP	LYS	TRP	SER	ASN	GLY	LYS
10	GLU	PHE	ASN	ASN	TRP	PHE	ASN	VAL	THR	GLY
11	SER	ASP	LYS	CYS	VAL	PHE	LEU	LYS	ASN	THR
12	GLU	VAL	SER	SER	MET	GLU	CYS	GLU	LYS	ASN
13	LEU	TYR	TRP	ILE	CYS	ASN	LYS	PRO	TYR	LYS