BMRB Entry 15209

Title:
Structure of the hDLG/SAP97 PDZ2 in complex with HPV-18 papillomavirus E6 peptide
Deposition date:
2007-04-10
Original release date:
2007-10-24
Authors:
Liu, Y.; Baleja, J.; Henry, G.; Hegde, R.
Citation:

Citation: Liu, Y.; Henry, G.; Hegde, R.; Baleja, J.. "Solution Structure of the hDLG/SAP97 PDZ2 domain and its mechanism for interaction with HPV-18 papillomavirus E6 protein"  Biochemistry 46, 10864-10874 (2007).

Assembly members:

Assembly members:
Disks_large_homolog_1, polymer, 97 residues, Formula weight is not available
C-terminal_HPV-18_E6_peptide, polymer, 6 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET30a(+)

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Disks_large_homolog_1: MEIKLIKGPKGLGFSIAGGV GNQHIPGDNSIYVTKIIEGG AAHKDGKLQIGDKLLAVNNV CLEEVTHEEAVTALKNTSDF VYLKVAKPTGSHHHHHH
C-terminal_HPV-18_E6_peptide: RRETQV

Data sets:
Data typeCount
13C chemical shifts332
15N chemical shifts93
1H chemical shifts662

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1hDlg PDZ2 domain1
2E6CT2

Entities:

Entity 1, hDlg PDZ2 domain 97 residues - Formula weight is not available

1   METGLUILELYSLEUILELYSGLYPROLYS
2   GLYLEUGLYPHESERILEALAGLYGLYVAL
3   GLYASNGLNHISILEPROGLYASPASNSER
4   ILETYRVALTHRLYSILEILEGLUGLYGLY
5   ALAALAHISLYSASPGLYLYSLEUGLNILE
6   GLYASPLYSLEULEUALAVALASNASNVAL
7   CYSLEUGLUGLUVALTHRHISGLUGLUALA
8   VALTHRALALEULYSASNTHRSERASPPHE
9   VALTYRLEULYSVALALALYSPROTHRGLY
10   SERHISHISHISHISHISHIS

Entity 2, E6CT 6 residues - Formula weight is not available

1   ARGARGGLUTHRGLNVAL

Related Database Links:

BMRB 17373 17942
PDB 2I0L 2M3M 2OQS 2X7Z 3RL8 4G69 4OAJ
REF XP_012432549

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks