BMRB Entry 15057

Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR15057

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Title:
Solution Structrue of C-terminal Bromodomain of Brd4
Deposition date:
2006-11-28
Original release date:
2008-06-24
Authors:
Liu, Y.; Wu, J.; Shi, Y.
Citation:

Citation: Liu, Y.; Wang, X.; Zhang, J.; Huang, H.; Ding, B.; Wu, J.; Shi, Y.. "Structural basis and binding properties of the second bromodomain of Brd4 with acetylated histone tails"  Biochemistry 47, 6403-6417 (2008).
PubMed: 18500820

Assembly members:

Assembly members:
Bromodomain-containing_protein_4, polymer, 114 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET22b(+)

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Bromodomain-containing_protein_4: EQLKCCSGILKEMFAKKHAA YAWPFYKPVDVEALGLHDYC DIIKHPMDMSTIKSKLEARE YRDAQEFGADVRLMFSNCYK YNPPDHEVVAMARKLQDVFE MRFAKMLEHHHHHH

Data sets:
Data typeCount
13C chemical shifts433
15N chemical shifts103
1H chemical shifts727

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Second bromodomain of Brd41

Entities:

Entity 1, Second bromodomain of Brd4 114 residues - Formula weight is not available

1   GLUGLNLEULYSCYSCYSSERGLYILELEU
2   LYSGLUMETPHEALALYSLYSHISALAALA
3   TYRALATRPPROPHETYRLYSPROVALASP
4   VALGLUALALEUGLYLEUHISASPTYRCYS
5   ASPILEILELYSHISPROMETASPMETSER
6   THRILELYSSERLYSLEUGLUALAARGGLU
7   TYRARGASPALAGLNGLUPHEGLYALAASP
8   VALARGLEUMETPHESERASNCYSTYRLYS
9   TYRASNPROPROASPHISGLUVALVALALA
10   METALAARGLYSLEUGLNASPVALPHEGLU
11   METARGPHEALALYSMETLEUGLUHISHIS
12   HISHISHISHIS

Related Database Links:

PDB 2I8N 2LSP 2MJV 2OUO 2YEM 3JVL 3JVM 4KV4 4Z93
REF XP_006524755 XP_006524756 XP_008763395 XP_011244845 XP_011382411

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks