BMRB Entry 11504

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PDB ID: 2rt5
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR11504
MolProbity Validation Chart

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Title:
Structure of SPOC domain of the human transcriptional corepressor SHARP
Deposition date:
2012-05-22
Original release date:
2013-12-02
Authors:
Mikami, Suzuka; Kanaba, Teppei; Mishima, Masaki
Citation:

Citation: Mikami, Suzuka; Kanaba, Teppei; Mishima, Masaki. "Structural Insights into the Recruitment of SMRT by the Corepressor SHARP under Phosphorylative Regulation"  Structure ., .-. (2013).
PubMed: 24268649

Assembly members:

Assembly members:
SHARP, polymer, 169 residues, 18471.535 Da.
SMRT, polymer, 8 residues, 1102.889 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pGEX6P-3

Entity Sequences (FASTA):

Entity Sequences (FASTA):
SHARP: VDMVQLLKKYPIVWQGLLAL KNDTAAVQLHFVSGNNVLAH RSLPLSEGGPPLRIAQRMRL EATQLEGVARRMTVETDYCL LLALPCGRDQEDVVSQTESL KAAFITYLQAKQAAGIINVP NPGSNQPAYVLQIFPPCEFS ESHLSRLAPDLLASISNISP HLMIVIASV
SMRT: YETLXDXE

Data sets:
Data typeCount
13C chemical shifts723
15N chemical shifts163
1H chemical shifts1137

Additional metadata:

  • Assembly
  • Samples and Experiments
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  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11
2entity_22

Entities:

Entity 1, entity_1 169 residues - 18471.535 Da.

1   VALASPMETVALGLNLEULEULYSLYSTYR
2   PROILEVALTRPGLNGLYLEULEUALALEU
3   LYSASNASPTHRALAALAVALGLNLEUHIS
4   PHEVALSERGLYASNASNVALLEUALAHIS
5   ARGSERLEUPROLEUSERGLUGLYGLYPRO
6   PROLEUARGILEALAGLNARGMETARGLEU
7   GLUALATHRGLNLEUGLUGLYVALALAARG
8   ARGMETTHRVALGLUTHRASPTYRCYSLEU
9   LEULEUALALEUPROCYSGLYARGASPGLN
10   GLUASPVALVALSERGLNTHRGLUSERLEU
11   LYSALAALAPHEILETHRTYRLEUGLNALA
12   LYSGLNALAALAGLYILEILEASNVALPRO
13   ASNPROGLYSERASNGLNPROALATYRVAL
14   LEUGLNILEPHEPROPROCYSGLUPHESER
15   GLUSERHISLEUSERARGLEUALAPROASP
16   LEULEUALASERILESERASNILESERPRO
17   HISLEUMETILEVALILEALASERVAL

Entity 2, entity_2 8 residues - 1102.889 Da.

YETL(SEP)D(SEP)E

1   TYRGLUTHRLEUSEPASPSEPGLU

Related Database Links:

PDB 1OW1 2RT5
DBJ BAA76773 BAB32786 BAG10400
EMBL CAB51072
GB AAD55931 AAI72907 AAK52750 EAW51756 EDL80993
REF NP_001258424 NP_055816 NP_062737 XP_002694185 XP_002750362
SP Q62504 Q96T58
TPG DAA21211
AlphaFold Q62504 Q96T58 Q9Y5U0

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SPARKY: Backbone or all simulated peaks