BMRB Entry 11078
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PDB ID: 2z5v
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR11078
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Ohnishi, Hidenori; Tochio, Hidehito; Kato, Zenichiro; Orii, Kenji; Li, Ailian; Kimura, Takeshi; Hiroaki, Hidekazu; Kondo, Naomi; Shirakawa, Masahiro. "Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4
signaling." Proc. Natl. Acad. Sci. U.S.A. 106, 10260-10265 (2009).
PubMed: 19506249
Assembly members:
MyD88 TIR domain, polymer, 149 residues, 17387.422 Da.
Natural source: Common Name: human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pGEX-5X-3
Entity Sequences (FASTA):
MyD88 TIR domain: TTLDDPLGHMPERFDAFICY
CPSDIQFVQEMIRQLEQTNY
RLKLCVSDRDVLPGTCVWSI
ASELIEKRCRRMVVVVSDDY
LQSKECDFQTKFALSLSPGA
HQKRLIPIKYKAMKKEFPSI
LRFITVCDYTNPCTKSWFWT
RLAKALSLP
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 454 |
| 15N chemical shifts | 134 |
| 1H chemical shifts | 850 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | MyD88 TIR domain | 1 |
Entities:
Entity 1, MyD88 TIR domain 149 residues - 17387.422 Da.
| 1 | THR | THR | LEU | ASP | ASP | PRO | LEU | GLY | HIS | MET | ||||
| 2 | PRO | GLU | ARG | PHE | ASP | ALA | PHE | ILE | CYS | TYR | ||||
| 3 | CYS | PRO | SER | ASP | ILE | GLN | PHE | VAL | GLN | GLU | ||||
| 4 | MET | ILE | ARG | GLN | LEU | GLU | GLN | THR | ASN | TYR | ||||
| 5 | ARG | LEU | LYS | LEU | CYS | VAL | SER | ASP | ARG | ASP | ||||
| 6 | VAL | LEU | PRO | GLY | THR | CYS | VAL | TRP | SER | ILE | ||||
| 7 | ALA | SER | GLU | LEU | ILE | GLU | LYS | ARG | CYS | ARG | ||||
| 8 | ARG | MET | VAL | VAL | VAL | VAL | SER | ASP | ASP | TYR | ||||
| 9 | LEU | GLN | SER | LYS | GLU | CYS | ASP | PHE | GLN | THR | ||||
| 10 | LYS | PHE | ALA | LEU | SER | LEU | SER | PRO | GLY | ALA | ||||
| 11 | HIS | GLN | LYS | ARG | LEU | ILE | PRO | ILE | LYS | TYR | ||||
| 12 | LYS | ALA | MET | LYS | LYS | GLU | PHE | PRO | SER | ILE | ||||
| 13 | LEU | ARG | PHE | ILE | THR | VAL | CYS | ASP | TYR | THR | ||||
| 14 | ASN | PRO | CYS | THR | LYS | SER | TRP | PHE | TRP | THR | ||||
| 15 | ARG | LEU | ALA | LYS | ALA | LEU | SER | LEU | PRO |
Related Database Links:
| BMRB | 15356 |
| PDB | 2JS7 2Z5V 4EO7 |
| DBJ | BAE89833 BAG55247 BAG55248 BAG55249 BAG55250 |
| GB | AAB49967 AAC50954 AAH13589 AAP36040 AAP36509 |
| REF | NP_001123935 NP_001124153 NP_001166039 NP_001266118 NP_001266529 |
| SP | B3Y678 B3Y679 B3Y680 B3Y681 B3Y682 |
| AlphaFold | B3Y678 B3Y679 B3Y680 B3Y681 B3Y682 |
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CSV: Backbone
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SPARKY: Backbone
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