BMRB Entry 6681

Title:
Solution Structure Of GIP In TFE/Water
Deposition date:
2005-06-09
Original release date:
2005-12-28
Authors:
Alana, I.; Parker, J.; Hewage, C.; Malthouse, J.; Flatt, P.; Gault, V.; O'Harte, F.
Citation:

Citation: Alana, I.; Hewage, C.; Malthouse, J.; Parker, J.; Gault, V.; O'Harte, F.. "NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide "  Biochem. Biophys. Res. Commun. 325, 281-286 (2005).
PubMed: 15522230

Assembly members:

Assembly members:
Gastric inhibitory polypeptide, polymer, 42 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Gastric inhibitory polypeptide: YAEGTFISDYSIAMDKIHQQ DFVNWLLAQKGKKNDWKHNI TQ

Data sets:
Data typeCount
1H chemical shifts277

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Gastric inhibitory polypeptide1

Entities:

Entity 1, Gastric inhibitory polypeptide 42 residues - Formula weight is not available

1   TYRALAGLUGLYTHRPHEILESERASPTYR
2   SERILEALAMETASPLYSILEHISGLNGLN
3   ASPPHEVALASNTRPLEULEUALAGLNLYS
4   GLYLYSLYSASNASPTRPLYSHISASNILE
5   THRGLN

Samples:

sample_1: Gastric inhibitory polypeptide 2 mM; TFE-d3 50%; H2O 50%

sample_cond_1: pH: 3.0; temperature: 298 K; pressure: 1 atm

Experiments:

NameSampleSample stateSample conditions
DQF-COSYnot availablenot availablenot available
2D TOCSYnot availablenot availablenot available
2D NOESYnot availablenot availablenot available

Software:

XWINNMR v3.5, Bruker - collection, processing

Sparky v3.110, Goddard and Kneller. - data analysis

CYANA v1.0.6, Guentert - structure solution

SYBYL v6.8.1, Tripos - refinement

NMR spectrometers:

  • Bruker DRX 900 MHz

Related Database Links:

BMRB 17330 17331 6245
PDB
GB AAA53192 AAA88043 AAH69100 AAH69663 AAH69686
REF NP_004114 XP_001091383 XP_001172671 XP_002806900 XP_002916897
SP P09681
AlphaFold P09681